TGen's Center for Rare Childhood Disorders (C4RCD) applies the latest tools of genomic medicine to provide answers for parents seeking to identify the disease or disorder affecting their child.
We harness the latest technologic leaps in genome sequencing to pinpoint the causes of rare childhood disorders that largely remain a mystery to modern medicine. Ours is a four-pronged effort, consisting of:
- Clinical evaluation and genomic diagnosis
- Optimizing conventional therapy
- Novel therapy development
- Community outreach
Each child will be clinically evaluated and have their genome tested, including the use of whole genome sequencing, which spells out the entire 3 billion letters of each individual’s DNA genetic code. If the sequencing reveals a genetic target, C4RCD scientists search the catalog of existing FDA-approved drugs in hopes of repurposing one to treat the rare disorder. If no drug exists, we work with experts to develop new treatments tailored for each child’s needs.